discussion question

Question Description

I’m working on a anatomy multi-part question and need guidance to help me learn.

1)Explain the reasoning behind these other signs and symptoms that Curie experienced. Assume her blood group was A negative. Which blood groups can she receive? Which blood groups can she not receive?

Fatigue, lightheadedness, and a fast heartbeat are signs of anemia, which is characterized by a reduction in red blood cells. Reduced RBCs result in less oxygen being transported to tissues. Recurring and prolonged infections indicate the presence of WBCs. Additionally, symptoms like easy bruising and prolonged bleeding from cuts point to a reduction in platelets. Marie Curie can only receive from people who are types A- or O- since she is type A-. Both antigen B and antigen D are guarded by her body. She cannot therefore receive from A+, B+, AB-, AB+, or O+ without causing a transfusion reaction. In that type of reaction, “your body produces antibodies to destroy the donor’s blood cells.” Your own blood and any blood you receive during a transfusion must be compatible.

Explain the reasoning behind these other signs and symptoms that Curie experienced.

Aplastic anemia is a hematopoietic dysfunction characterized by pancytopenia in which red blood cells, white blood cells, and platelets are all decreased due to decreased function and cellularity of bone marrow cells and replacement of bone marrow tissues with fat. Marie Curie was diagnosed with aplastic anemia due to radiation exposure. These other signs and symptoms are due to the failure of red blood cell function. Patients with coagulation disorders bruise easily. In severe forms, spontaneous bleeding may occur throughout the body. Easy bruising and prolonged bleeding from cuts is signs of coagulation disorders because of low platelet functions.

Assume her blood group was A negative. Which blood groups can she receive? Which blood groups can she not receive? Explain why.

Your immune system ignores the surface antigens on your own red blood cells. A cross-reaction occurs when an antibody meets its specific surface antigen. To avoid cross-reactions, the blood types of the donor and recipient must be compatible. Marie Curie can only receive from A negative and O negative blood groups.

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