BIOL Human Genome Editing

Question Description

I’m working on a biology discussion question and need an explanation and answer to help me learn.

1. In this article by NIH director Francis Collins (https://fortune.com/2020/03/08/hiv-sickle-cell-gene-therapy/), he details the ambitious plan to wipe out sickle cell anemia and HIV, with the majority of those impacted, and therefore those who would benefit, living in sub-Saharan Africa, with limited access to resources. What are the current hurdles in helping these populations? How does CRISPR as a gene editing tool offer promise? Additionally, what ethical rules must be considered with these populations?

2. In this article by Francis Collins (https://www.discovermagazine.com/health/nih-director-on-human-gene-editing-we-must-never-allow-our-technology-to), the Director of the NIH describes the scientific desire to forge ahead, despite a moratorium on genome editing. Why might scientists want to pursue these activities, even though there is a moratorium? Are there scenarios in which forging ahead might be acceptable?

Explanation & Answer:

400 words

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